Mark G. Shrime, MD

Assistant Professor—Department of Otolaryngology/Head and Neck Surgery
Email:  mark.shrime@bmc.org
Telephone:  617 | 638.7933
Fax:  617 | 638.7965

Clinical Interests:
Head and neck cancer; Microvascular reconstructive surgery; Skin cancers in the head and neck; Thyroid and Parathyroid diseases; Bony tumors in the head and neck; Airway disorders; Traumatic injuries to the head and neck.

Disorders in which Dr. Shrime has special expertise:

• Cancers of the tongue, tonsil, throat, larynx, nasopharynx, and other areas in the head and neck
• Skin cancers in the head and neck
• Bony tumors in the head and neck
• Congenital masses in the head and neck
• Microvascular and plastic reconstructive surgery in the head and neck
• Microvascular reconstructive surgery of defects throughout the body
• Thyroid cancer (papillary, follicular, anaplastic, and medullary)
• Thyroid masses and tumors
• Parathyroid adenomas and enlargements
• Endocrine disorders in the head and neck
• Trauma to the head and neck
• Hoarseness

Board Certification:
American Board of Otolaryngology/Head and Neck Surgery—2008

Academic Appointments:
Assistant Professor of Otolaryngology
Boston University School of Medicine
Boston, Massachusetts
2009 – present

Clinical Staff Appointments:
Staff Surgeon
Mercy Ships, m/v Africa Mercy
2008, Monrovia, Liberia
2009, Cotonou, Benin

Education:
Masters of Public Health
Harvard School of Public Health
Boston, MA
2009­ – present

Fellowship
Microvascular reconstructive surgery
University of Toronto Health Network
Toronto, ON
2008
Fellowship director:  Dr. Ralph Gilbert

Fellowship
Head and neck oncologic and endocrine surgery
University of Toronto Health Network
Toronto, ON
2006-2007
Fellowship directors:  Drs. Patrick Gullane, Jeremy Freeman, and Ralph Gilbert

Residency
Otolaryngology/Head and Neck Surgery
New York Presbyterian Hospital
Columbia University Medical Center
Cornell University Medical Center
Memorial-Sloan Kettering Cancer Center
New York, NY
2002-2006
Chairmen:  Drs. Lanny Close and Michael Stewart

Internship
General Surgery
New York Presbyterian Hospital
Columbia University Medical Center
New York, NY
2001-2002
Chairman:  Dr. Mark Hardy

Medical School
University of Texas, Southwestern Medical School
Dallas, TX
1996-2001

Bachelor of Arts
Molecular Biology—summa cum laude
Princeton University
Princeton, NJ
1992-1996

Awards and Honors:

• The Arnold P. Gold Foundation, Humanism and Excellence in Teaching Award, 2005
• Summa cum laude, Princeton University, 1996
• Alpha Omega Alpha, University of Texas, Southwestern Medical School, 2001
• First place poster presentation, Triological Society, 2007
• American College of Surgeons, Resident Teaching Award (nominee), 2003
• Research Travel Grants, 2003, 2005, 2006
• The John Q. Adams Center for the History of Otolaryngology Research Grant, 2003

Professional Memberships:

• Humanitarian Efforts Committee, American Academy of Otolaryngology, 2009 – present
• Editorial Reviewer, Laryngoscope, 2007 – present
• Editorial Reviewer, Head and Neck, 2007 – present
• American Head and Neck Society
• American Academy of Otolaryngology
• Alpha Omega Alpha Medical Honor Society
• National Arab-American Medical Association

Book Chapters:

1. Shrime MG, Goldstein DP, Irish JC, Gullane PJ.  Complications of Lip Surgery.  In:  Eisele DW (ed).  Complications of Head and Neck Surgery, 2e.  Elsevier, 2009. pp 251-256.

2. Kraus, DH, Shrime MG.  Oral Cavity Neoplasms.  In:  Snow JB and Ballenger JJ (eds).  Ballenger’s Otorhinolaryngology Head and Neck Surgery: Head and Neck Surgery, 17e.  BC Decker 2009.  pp 1091-1104.

3. Shrime MG, Keller J.  Pediatric allergic rhinitis and acute and chronic sinusitis.  In: Burg FD, Ingelfinger JR, Polin RA, Gershon A (eds). Current Pediatric Therapy, 18e.  WB Saunders Company, 2006.  pp 1114-1118.

4. Goldstein DP, Shrime MG, Cummings B, Gullane PJ.  Paragangliomas of the Head and Neck.  In Hanna EY and DeMonte F (eds). Comprehensive Management of Skull Base Tumors. Informa HealthCare, 2008.  pp 539-556.

5. Shrime MG, Manolidis SM.  Orbital Neoplasms.  In:  Manolidis SM.  Orbital Surgery.  Plural Publishing.  In press

Publications:

1. Shrime MG, Gullane PJ, Dawson L, Kim J, Gilbert RW, Irish JC, Brown DH, Goldstein DP.  The impact of adjuvant radiotherapy on survival in T1-2N1 squamous cell carcinoma of the oral cavity.  Accepted for publication­:  Archives of Otolaryngology—Head and Neck Surgery

2. Shrime MG, Bachar G, Lea J, Volling C, Ma C, Gullane PJ, Gilbert RW, Irish JC, Brown DH, Goldstein DP.  Nodal ratio as an independent predictor of survival in squamous cell carcinoma of the oral cavity.  Head and Neck 2009. Epub ahead of print.

3. Shrime MG, Gilbert RW.  Reconstruction of the midface and maxilla.  Facial Plastic Surgery Clinics 2009. 17(2):211-223.

4. Shrime MG, Ma CS, Gullane PJ, Gilbert RW, Irish JC, Brown DH, Goldstein DP.  The impact of nodal ratio on survival in squamous cell carcinoma of the oral cavity.  Head and Neck 2009. 31(9):1129-1136.  Epub 4 April 2009.

5. Shrime MG, Goldstein DP, Seaberg RM, Sawka AM, Rotstein L, Freeman JL, Gullane PJ.  Cost-effective management of low-risk papillary thyroid cancer.  Archives of Otolaryngology—Head and Neck Surgery 2007. 133(12):1245-1253. Included in Audio Digest—Otolaryngology, 41(4), 21 July 2008

6. Shrime MG, Johnson PE, Stewart MG.  Cost-effective diagnosis of ingested foreign bodies.  Laryngoscope 2007. 117(5):785-793.

7. Shrime MG, Tabaee A, Rickert S, Hsu AK, Close LG.  Synechia formation following endoscopic sinus surgery and middle turbinate medialization.  American Journal of Rhinology 2007. 21(2):174-179.

8. Shrime MG, Wilson TB, Eisig SB, Haddad J.  Intraosseous schwannoma of the mandible.  Archives of Otolaryngology—Head and Neck Surgery 2007. 133(2):194, 196.

9. Goldstein DP, Shrime MG, Irish JC.  Hoarseness:  the good, the bad, and the ugly. The Canadian Journal of Diagnosis 2007.  24(2):84-88.

10. Jeremic G, Shrime MG, Irish JC, Gilbert RW, Goldstein DP.  The microvascular anastomotic device and its role in free tissue transfer.  University of Toronto Medical Journal 2006. 84(1):51-54.

11. Krespi Y, Shrime MG, Kacker A.  The relationship between oral malodor and volatile sulfur compound-producing bacteria.  Otolaryngology—Head and Neck Surgery 2006.  135(5):671-676.

12. Tabaee A, Hsu AK, Shrime MG, Rickert S, Close LG. Quality of life and complications following image-guided endoscopic sinus surgery.  Otolaryngology—Head and Neck Surgery 2006.  135(1):76-80.

13. Shrime MG, Kacker A, Bent J, Ward RF.  Fourth branchial complex anomalies:  A case series.  International Journal of Pediatric Otorhinolaryngology 2003; 67:1227-1233. Selected for inclusion in the American Academy of Otolaryngology 2005-2006 Home Study Course, Section 1

14. Shrime MG.  Understanding Nm23 actions and interactions through structural and biologic modeling.  Princeton University, Undergraduate Thesis, 1996

Presentations:

1.  Shrime MG, Bachar G, Lea J, Volling C, Ma C, Gullane PJ, Gilbert RW, Irish JC, Brown DH, Goldstein DP.  Nodal ratio as an independent predictor of survival in squamous cell carcinoma of the oral cavity.  Presented at the International Academy of Oral Oncology, July 2009, Toronto

2. Shrime MG.  The Right to Look Human:  Practicing Medicine in the Developing World.  Presented at Wachovia Securities, The Seagram Building, May 2009, New York City, on behalf of Mercy Ships

3. Shrime MG.  The Right to Look Human:  Head and Neck Surgery in the Developing World. Department of Otolaryngology Fellowship Rounds, December 2008, Toronto

4. Shrime MG, Goldstein DP, Seaberg RM, Freeman JL, Gullane PJ.  Cost-effective management of low-risk papillary thyroid cancer. Presented at the American Head and Neck Society, April 2007, San Diego

5. Shrime MG, Goldstein DP, Le L, Gullane PJ.  The impact of postoperative radiotherapy and the extent of neck dissection on T1-2N1 squamous cell carcinoma of the oral cavity. Presented at the International Academy of Oral Oncology, May 2007, Amsterdam

6. Shrime MG, Johnson PE, Stewart MG.  Cost-effective diagnosis of ingested foreign bodies.  First-place poster presentation at the Combined Otolaryngology Fall Meeting, February 2007, Florida

7. Shrime MG.  Depression in Head and Neck Cancer.
   Department of Otolaryngology Fellowship Rounds, November 2006, Toronto
   

8. Shrime MG, Tabaee A, Rickert S, Hsu AK, Close LG.  Synechia formation following endoscopic sinus surgery and middle turbinate medialization. Presented at the Combined Otolaryngology Spring Meeting, May 2006, Chicago

9. Tabaee A, Hsu AK, Shrime MG, Rickert S, Close LG. Quality of life and complications following image-guided endoscopic sinus surgery. Presented at the Triologic Society, Eastern Section, January 2006, Toronto, ON.

10. Shrime MG, Kacker A, Orjuela AF, Xiang Z, Anand VK.  Dysregulation of the apoptotic pathway in chronic rhinosinusitis.
    Presented at the Triologic Society, Eastern Section, January 2006, Toronto, ON

11. Ahn JA, Grunstein E, Shrime MG, Weiss G, Lin H, Ambron R.  The role of retrograde signal peptides in facial nerve regeneration.
    Presented at the American Academy of Facial Plastic and Reconstructive Surgery, September 2005, Los Angeles

12. Anand VK, Manarey C, Shrime MG, Kacker A.  Real-time image-guided endoscopic sinus surgery using the FluoroCAT technology.  Presented at the Combined Otolaryngological Spring Meetings, May 2004.

13. Shrime MG.  Facial Plastic Surgery and the American Civil War.
    Presented at the AAO-HNS National Meeting, 22 September 2003, Jacksonville, FL.

14. Shrime MG, McClay JE, Biavati M, et al.  Gastroesophageal reflux and true vocal cord nodules.  Presented at the American Society of Pediatric Otolaryngologists, Friday, 11 May 2001.

Research Interests:

• Outcomes in head and neck cancer
• Cost-effective diagnosis and treatment of otolaryngologic conditions
• Medical education and training in resource-poor settings